Activation of FGF signaling mediates proliferative and osteogenic differences between neural crest derived frontal and mesoderm parietal derived bone.

As a culmination of efforts over the last years, our knowledge of the embryonic origins of the mammalian frontal and parietal cranial bones is unambiguous.Progenitor cells that subsequently give rise to frontal bone are of neural crest origin, while wickelfalzrohre parietal bone progenitors arise from paraxial mesoderm.Given the unique qualities of

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Numerical investigation of the behaviour of bolted and welded top and seat angle connection in progressive collapse of steel structures

After failure of a column in structure by an abnormal loading, undesirable performance and damage of connections of the beams connected to the top of this column, can lead to the local failure of floor and in turn result in progressive collapse in the structure.Accordingly, the best method for rehabilitation of the structure against this incident i

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Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53

Mutation in TP53 is a common genetic alteration in human cancers.Certain tumor associated p53 missense mutants acquire gain-of-function (GOF) properties and confer oncogenic phenotypes including enhanced chemoresistance.The colorectal cancers (CRC) harboring mutant p53 are generally aggressive in nature and difficult to treat.To identify a potentia

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The ideological aspect of intersemiotic translation and montage

The Estonian film The Last Relic offers an interesting case of ideological intersemiotic translation.At the same time, it is an innovative film from the point of view of text sun decal for wall composition as well as combination of traditional montage with intersemiotic montage in which the speech of the heroes, the messages of the songs and repeti

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